DailyBrief

Wednesday, September 30, 2026

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In depthBriefs

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AIHacker News · Best

Dots: Always-on agents

Article URL: https://openai.com/index/introducing-dots/ Comments URL: https://news.ycombinator.com/item?id=49896604 Points: 463 # Comments: 351

AIHacker News · Best

macOS Golden Gate Is a Buggy Mess

Article URL: https://www.squareorbits.com/blog/2026/09/macos-golden-gate-is-a-buggy-mess/ Comments URL: https://news.ycombinator.com/item?id=49894005 Points: 436 # Comments: 314

TechHacker News

Livenerf: Has Opus 5.5 been nerfed yet?

Article URL: https://github.com/ninjahawk/livenerf Comments URL: https://news.ycombinator.com/item?id=49901736 Points: 187 # Comments: 94

TechHacker News

PS5 Relapse Exploit

Article URL: https://github.com/ntfargo/Relapse-Exploit Comments URL: https://news.ycombinator.com/item?id=49895304 Points: 232 # Comments: 125

TechArs Technica

Most powerful obesity drug yet: People lost up to 25% of weight in trial

Researchers published late-stage clinical trial data today for the latest obesity drug, retatrutide—expected to be the most powerful formula yet—and the results appear in line with high expectations. Patients with obesity on the highest retatrutide dose lost an average of 25 perc

TechArs Technica

Protests against OpenAI get increasingly creative

Two artists from a Bay Area studio unveiled What Iceberg? , a table-sized installation placed at the public entrance to an OpenAI developer event in San Francisco on Tuesday. According to a description of the piece, the 5-foot-tall sculpture "shows OpenAI's leaders and investors

TechArs Technica

AMD acquires World Labs AI startup, upping the ante against Nvidia

Chipmaker AMD and world models company World Labs announced that AMD will acquire the AI company by the end of the year, pending regulatory approval. The transaction is valued at $8.2 billion. In 2024, computer vision scientist Fei-Fei Li founded World Labs with fellow researcher

BioSTAT

STAT+: At MAHA Summit, a grassroots movement goes corporate

WASHINGTON — The Make America Healthy Again movement has changed, if Tuesday’s MAHA Summit is any indication. The insurgent movement that coalesced around mistrust of the health system and corporate influence put on a summit where industry leaders promoted their work under the MA

BioSTAT

STAT+: PhRMA taps Eric Cantor as new CEO

WASHINGTON — Eric Cantor, a former GOP House majority leader, will be the next CEO of PhRMA, the lobbying group announced Tuesday. As head of the brand drug industry’s top lobbying group, Cantor will face mounting political pressure on drug prices and an increasingly populist moo

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